COR659

SKU: orb1303954

Description

COR659 is a 2-acylaminothiophene derivative that functions as a GABAB receptor positive allosteric modulator and a cannabinoid CB1 receptor antagonist/inverse agonist. It has been shown to reduce alcohol and chocolate self-administration in rodent models, supporting its use in preclinical research on addiction and reward-related behaviors.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 544450-68-2
• MW: 337.82
• Purity: 99.56% (May vary between batches)
• Formula: C₁₆H₁₆ClNO₃S
• SMILES: CCc1c(C)sc(NC(=O)c2ccc(Cl)cc2)c1C(=O)OC
• Target: GABA Receptor,Cannabinoid Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.92 mM);DMSO:33.33 mg/mL (98.66 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COR659, COR-659, COR 659, chocolate, CB1, Cannabinoid Receptor, CannabinoidReceptor, alcohol, GABA Receptor, GABAReceptor, GABAB, Gamma-aminobutyric acid Receptor, Inhibitor, inhibit, sucrose, γ-Aminobutyric acid Receptor

Quick Database Links

Gene Symbol

GABA Receptor,Cannabinoid Receptor