Corynoxine

SKU: orb1301332

Description

Corynoxine is a tetracyclic oxindole alkaloid derived from Uncaria macrophylla. It functions as an autophagy enhancer, facilitating the clearance of α-synuclein via Akt/mTOR pathway inhibition, making it a useful research tool for studying neurodegenerative mechanisms in cellular models.

Research Area

Cell Biology

Key Properties

• CAS Number: 6877-32-3
• MW: 384.47
• Purity: 96.83% (May vary between batches)
• Formula: C₂₂H₂₈N₂O₄
• SMILES: CC[C@@H]1CN2CC[C@]3([C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC)C(=O)Nc1ccccc31
• Target: Autophagy
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.2 mM);DMSO:55 mg/mL (143.05 mM);Ethanol:50 mg/mL (130.05 mM);H2O:Insoluble

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Corynoxine, Autophagy, alkaloid, inhibit, mTOR, macrophylla, Inhibitor, synuclein Akt, oxindole, Uncaria, tetracyclic

Quick Database Links

Gene Symbol

Autophagy