CU-T12-9

SKU: orb1308425

Description

CU-T12-9 is a potent and selective TLR1/2 heterodimer agonist (EC50 = 52.9 nM) that activates the NF-κB pathway, inducing proinflammatory cytokines. This activity makes it a valuable research tool for studying innate/adaptive immunity in models of infection, vaccination, and inflammatory diseases.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 1821387-73-8
• MW: 362.31
• Purity: 99.84% (May vary between batches)
• Formula: C₁₇H₁₃F₃N₄O₂
• SMILES: CNc1ccc(cc1-n1cnc(c1)-c1ccc(cc1)C(F)(F)F)[N+]([O-])=O
• Target: TLR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.8 mM);DMSO:250 mg/mL (690.02 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, infectious, inflammatory, influenza, pancreatic, obesity, Inhibitor, breast, diseases, CU T12 9, CUT129, CU-T-12-9, CU-T12-9, asthma, bladder, carcinoma, cancer, TLR, TLR1, TLR2, TLR1/2, Toll-like Receptor (TLR), specific

Quick Database Links

Gene Symbol

TLR