CUDC-101

SKU: orb1304532

Description

CUDC-101 is a multi-targeted small molecule inhibitor with potent activity against HDAC, EGFR, and HER2, exhibiting IC50 values of 4.4 nM, 2.4 nM, and 15.7 nM, respectively. It has been investigated in preclinical cancer research for its potential to overcome resistance and has shown efficacy in both cellular and animal models of various solid tumors.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 1012054-59-9
• MW: 434.49
• Purity: >98%
• Formula: C₂₄H₂₆N₄O₄
• SMILES: N(C=1C2=C(C=C(OC)C(OCCCCCCC(NO)=O)=C2)N=CN1)C3=CC(C#C)=CC=C3
• Target: Kinase
• Solubility: Soluble in DMSO (up to 25 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CUDC 101, CUDC101, CUDC-101, HDAC1, HDAC3, HDAC2, HDAC4, HDAC10, HDAC8, HDAC5, HDAC, HDAC7, HDAC9, HDAC6, HER2, HER1, Histone deacetylases, Epidermal growth factor receptor, ErbB-1, EGFR, Inhibitor, inhibit

Quick Database Links

Gene Symbol

Kinase