Cycloguanil hydrochloride

SKU: orb1220994

Description

Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 152-53-4
• MW: 288.18
• Purity: >98% (HPLC)
• Formula: C₁₁H₁₄ClN₅.ClH
• SMILES: Cl.CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)cc1
• Target: Parasite
• Solubility: DMSO: 20 mg/mL (69.4 mM);Water: 5 mg/mL (17.35 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Chloroguanide Triazine

Quick Database Links

Gene Symbol

Parasite