D-Biotin

SKU: orb1224565

Description

Biotin is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.(In Vitro):Biotin exhibits higher affinity on breast cancer (T47D) cells over normal mammary epithelial (MCF-12A) cells, with Kms of 9.24 μM and 53.1 μM, respecetively.Biotin (0.09-100 μM; 0-70 min) is dose-dependently uptake by T47D cells with Vmax of 27.34 pmol/mg protein/min.Biotin (1-1000 nM; 24 h) exerts function in the recovery of 7β-OHC (50 μM)-induced cell death and reduces cell adhesion.(In Vivo):Biotin (15 mg/kg/d; p.o.; 12 d) improves nephrotoxicity in streptozotocin-induced (150 mg/kg; i.p.) diabetic mice.Biotin (0.012 mg/kg/d; p.o.; 70 d) deficiency impaires the immune function of the head kidney, spleen and skin in fish with inadequate administration dose.

Key Properties

• CAS Number: 58-85-5
• MW: 244.31
• Purity: >98% (HPLC)
• Formula: C₁₀H₁₆N₂O₃S
• SMILES: C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2
• Target: Vitamin
• Solubility: DMSO: 49 mg/mL (200.56 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

D-Biotin | NSC 63865 | Vitamin B7

Quick Database Links

Gene Symbol

Vitamin