Dabuzalgron

SKU: orb1309790

Description

Dabuzalgron (Ro 115-1240) is a selective α1A-adrenoceptor agonist used in research for urinary incontinence. Studies indicate it also exhibits a cardioprotective role in models of doxorubicin-induced cardiotoxicity by preserving mitochondrial function, relevant for in vivo and in vitro pharmacological investigations.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 219311-44-1
• MW: 317.79
• Purity: 98.35% (May vary between batches)
• Formula: C₁₂H₁₆ClN₃O₃S
• SMILES: Cc1c(OCC2=NCCN2)ccc(Cl)c1NS(C)(=O)=O
• Target: Adrenergic Receptor,Apoptosis
• Solubility: DMSO:25 mg/mL (78.67 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.29 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dabuzalgron, Cell, Beta Receptor, AdrenergicReceptor, Adrenergic Receptor, Apoptosis, mitochondrial, inhibit, incontinence, death, Inhibitor, membrane, α1A-adrenergic receptor, urinary, Ro 115-1240, potential

Quick Database Links

Gene Symbol

Adrenergic Receptor,Apoptosis