Daphnetin

SKU: orb1304931

Description

Daphnetin (7,8-Dihydroxycoumarin) is a natural protein kinase inhibitor targeting EGFR, PKA, and PKC. It also possesses antioxidant and anti-inflammatory properties, supporting its investigation in cellular assays and animal models for oncology and inflammatory disease research.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 486-35-1
• MW: 178.14
• Purity: 97.47% (May vary between batches)
• Formula: C₉H₆O₄
• SMILES: Oc1ccc2ccc(=O)oc2c1O
• Target: Parasite,PKA,Akt,Bcl-2 Family,mTOR,Reactive Oxygen Species,EGFR,PARP,ROS,Apoptosis,Caspase,Autophagy,AMPK,PKC
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.23 mM);DMSO:50 mg/mL (280.68 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Daphnetin, Daphnetol, 7,8-Dihydroxycoumarin, A2780 cells, AMP-activated protein kinase, Akt, Caspase, Bcl-2 Family, Autophagy, Apoptosis, AMPK, inflammation, mTOR, inhibit, PARP, Parasite, Epidermal growth factor receptor, ErbB-1, EGFR, Inhibitor, HER1, Mammalian target of Rapamycin, schizontocidal, poly ADP ribose polymerase, Protein kinase C, Protein kinase B, protein kinase, Protein kinase A, PKC, PKB, PKA, Reactive Oxygen Species

Quick Database Links

Gene Symbol

Parasite,PKA,Akt,Bcl-2 Family,mTOR,Reactive Oxygen Species,EGFR,PARP,ROS,Apoptosis,Caspase,Autophagy,AMPK,PKC