Deferoxamine Mesylate

SKU: orb1307936

Description

Deferoxamine Mesylate is a small molecule iron chelator that inhibits ferroptosis by sequestering free iron and reducing its accumulation. It is widely used in research to study iron overload, HIF-1α stabilization, and apoptosis in both cellular and animal models of diseases like cancer and neurodegeneration.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 138-14-7
• MW: 656.79
• Purity: 94.68% (May vary between batches)
• Formula: C₂₆H₅₂N₆O₁₁S
• SMILES: CS(O)(=O)=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN
• Target: Autophagy,Reactive Oxygen Species,Akt,ROS,Ferroptosis,Mitophagy,Beta Amyloid,HIF/HIF Prolyl-Hydroxylase,Apoptosis
• Solubility: DMSO:127.5 mg/mL (194.13 mM);H2O:20.83 mg/mL (31.71 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

β Amyloid, βAmyloid, TAMSCs, SH-SY5Y, Iron, Mitophagy, neovascularization, Ferroptosis, HIF ProlylHydroxylase, HIF, HIF/HIFProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF/HIF ProlylHydroxylase, HIFProlylHydroxylase, MEFs, Alzheimer's disease, b Amyloid, Autophagy, Amyloid-β, BMMSCs, bAmyloid, diabetes mellitus, DFOM, Desferrioxamine B mesylate, Deferoxamine, Deferoxamine Mesylate, COVID-19, Beta Amyloid, BetaAmyloid

Quick Database Links

Gene Symbol

Autophagy,Reactive Oxygen Species,Akt,ROS,Ferroptosis,Mitophagy,Beta Amyloid,HIF/HIF Prolyl-Hydroxylase,Apoptosis