WP-1130

SKU: orb1300890

Description

Degrasyn (WP1130) is a small molecule inhibitor that targets specific deubiquitinases (DUBs) including USP5 and USP9x, and also inhibits Bcr-Abl and JAK2-STAT signaling. It is utilized in research to study protein degradation pathways and oncogenic signaling in both cellular and animal models of cancer and inflammation.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 856243-80-6
• MW: 384.28
• Purity: >98%
• Formula: C₁₉H₁₈BrN₃O
• SMILES: CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1
• Target: DUB (Deubiquitinating enzyme)
• Solubility: Soluble in DMSO (up to 45 mg/ml), or in Ethanol (up to 25 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Degrasyn

Quick Database Links

Gene Symbol

DUB (Deubiquitinating enzyme)