Dexamethasone

SKU: orb1309846

Description

Dexamethasone is a potent synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties, acting as a glucocorticoid receptor agonist. It is widely used in research to model conditions like depression and muscle atrophy in vivo, and to study cytokine modulation and autophagy in cellular experiments. Its mechanisms include inhibiting inflammatory exosome release and suppressing LPS-induced macrophage activation.

Research Area

Cell Biology, Immunology & Inflammation, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 50-02-2
• MW: 392.5
• Purity: >98%
• Formula: C₂₂H₂₉FO₅
• SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
• Target: Transcription factor
• Solubility: Soluble in DMSO (up to 40 mg/ml).

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dexamethasone, Complement System, ComplementSystem, CD18, CD62L, CD11b, ADC Cytotoxin, ADCCytotoxin, Autophagy, Antibiotic, Bacterial, MK125, MK-125, neutrophils, NSC34521, NSC-34521, Mitophagy, Mitochondrial Autophagy, MK 125, ILReceptor, monocytes, IL Receptor, IL receptor, inhibit, NSC 34521, glucocorticoid, GlucocorticoidReceptor, Glucocorticoid Receptor, Inhibitor, Hexadecadrol, Prednisolone F, receptor, SARSCoV, SARS-CoV, SARS coronavirus

Quick Database Links

Gene Symbol

Transcription factor