Dexamethasone palmitate

SKU: orb1308392

Description

Dexamethasone palmitate is a lipophilic prodrug and glucocorticoid receptor agonist with anti-inflammatory properties, exhibiting 47-fold lower receptor affinity than dexamethasone. It is utilized in research to study targeted glucocorticoid delivery and anti-inflammatory effects in both cellular and animal models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 14899-36-6
• MW: 630.87
• Purity: 98.08% (May vary between batches)
• Formula: C₃₈H₅₉FO₆
• SMILES: [H][C@@]12C[C@@H](C)[C@](O)(C(=O)COC(=O)CCCCCCCCCCCCCCC)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
• Target: Others,Glucocorticoid Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.93 mM);DMSO:250 mg/mL (396.28 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

lipophilic, inhibit, inflammation, Inhibitor, GlucocorticoidReceptor, Glucocorticoid Receptor, cytokine, DXP, Dexamethasone palmitate, Dexamethasone, prodrug, RAW 264.7, VEGF

Quick Database Links

Gene Symbol

Others,Glucocorticoid Receptor