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DHODH-IN-16

SKU: orb1303302

Description

DHODH-IN-16 is a potent and selective small molecule inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 of 0.396 nM. This compound is a valuable chemical probe for studying pyrimidine biosynthesis in cellular and biochemical assays, supporting research in immunology, oncology, and virology.

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Images & Validation

Key Properties

CAS Number2511248-11-4
MW436.48
Purity99.64% (May vary between batches)
FormulaC24H25FN4O3
SMILESCCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)C(C)C)c1=O
TargetDNA/RNA Synthesis,Dehydrogenase
SolubilityDMSO:95 mg/mL (217.65 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.56 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DHODH IN 16, DHODH, DHODHIN16, DHODH-IN-16, Dihydroorotate Dehydrogenase, DNA/RNA Synthesis, antiproliferative, inhibit, Inhibitor
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Protocol Information

DHODH-IN-16 (orb1303302)

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Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 220.00
1 ml x 10 mM (in DMSO)
$ 230.00