Dinaciclib

SKU: orb1307130

Description

Dinaciclib (SCH 727965) is a potent and selective inhibitor of CDK1, CDK2, CDK5, and CDK9 with antitumor activity. It has been investigated in vitro and in vivo for oncology research, particularly in studies of cell cycle arrest and transcription inhibition in various cancer models.

Research Area

Cell Biology

Key Properties

• CAS Number: 779353-01-4
• MW: 396.49
• Purity: 98.21% (May vary between batches)
• Formula: C₂₁H₂₈N₆O₂
• SMILES: N(CC1=CN(=O)=CC=C1)C=2N3C(N=C(C2)N4[C@H](CCO)CCCC4)=C(CC)C=N3
• Target: Apoptosis,CDK
• Solubility: DMSO:130 mg/mL (327.88 mM);Ethanol:8 mg/mL (20.18 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.61 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dinaciclib, Cyclin dependent kinase, CDK5, CDK9, CDK, CDK1, CDK2, Apoptosis, inhibit, Inhibitor, SCH727965, SCH-727965, SCH 727965, PS095760, PS-095760, PS 095760

Quick Database Links

Gene Symbol

Apoptosis,CDK