Diquafosol tetrasodium

SKU: orb1299832

Description

Diquafosol Tetrasodium (INS365) is a selective P2Y2 receptor agonist used in ophthalmic research. It promotes mucin and fluid secretion from ocular surface cells, enhancing tear film stability in models of dry eye disease. This mechanism supports its investigation in both in vitro cellular assays and in vivo animal studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 211427-08-6
• MW: 878.23
• Purity: 98.25% (May vary between batches)
• Formula: C₁₈H₂₂N₄Na₄O₂₃P₄
• SMILES: O=c1ccn(C2OC(COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OCC3OC(n4ccc(=O)[nH]c4=O)C(O)C3O)C(O)C2O)c(=O)[nH]1.[Na+].[Na+].[Na+].[Na+]
• Target: P2Y Receptor
• Solubility: DMSO:Insoluble;H2O:247.5 mg/mL (281.82 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Diquafosol, Diquafosol tetrasodium, inhibit, Inhibitor, INS 365, INS365, INS-365, P2Y, P2YReceptor, P2Y Receptor, P2Y2 receptor

Quick Database Links

Gene Symbol

P2Y Receptor