Donitriptan

SKU: orb1309750

Description

Donitriptan is a potent and selective agonist for 5-HT1B and 5-HT1D receptors, exhibiting pKi values of 9.4 and 9.3, respectively. This compound is a valuable research tool for studying serotonergic pathways in models of migraine and neurovascular disorders, applicable in both in vitro and in vivo experimental settings.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 170912-52-4
• MW: 403.48
• Purity: 98.34% (May vary between batches)
• Formula: C₂₃H₂₅N₅O₂
• SMILES: NCCc1c[nH]c2ccc(OCC(=O)N3CCN(CC3)c3ccc(cc3)C#N)cc12
• Target: 5-HT Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.18 mM);DMSO:245 mg/mL (607.22 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, 5-HT1B, 5-HT1D, 5-HT1D Receptor, 5-HT1B Receptor, 5-HT Receptor, 5HT Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, Donitriptan, pki, Serotonin Receptor

Quick Database Links

Gene Symbol

5-HT Receptor