DTHIB

SKU: orb1298577

Description

DTHIB is a potent small molecule inhibitor of HSF1 signaling. It robustly suppresses the HSF1-driven oncogenic transcriptional program and inhibits the proliferation of prostate cancer cells in vitro. This compound is a valuable research tool for investigating HSF1 pathway biology and cancer therapeutics.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 897326-30-6
• MW: 309.68
• Purity: 98.86% (May vary between batches)
• Formula: C₁₃H₉ClFN₃O₃
• SMILES: [O-][N+](=O)c1cc(NC(=O)Nc2ccc(F)cc2)ccc1Cl
• Target: HSP
• Solubility: 10% DMSO+90% Saline:2 mg/mL (6.46 mM);DMSO:25 mg/mL (80.73 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cancer, anticancer, degradation, DTHIB, HSP, HSP70, HSP90, HSP27, HSF1, Heat shock proteins, nuclear, inhibit, Inhibitor, prostate

Quick Database Links

Gene Symbol

HSP