E 64c

SKU: orb1300647

Description

E-64c (EP 475) is a cell-permeable, irreversible inhibitor of cysteine proteases. This compound is widely used in biochemical research to study protease function in both cellular (in vitro) and animal (in vivo) models of diseases such as muscular dystrophy and cancer.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 76684-89-4
• MW: 314.38
• Purity: 98.73% (May vary between batches)
• Formula: C₁₅H₂₆N₂O₅
• SMILES: CC(C)CCNC(=O)C(CC(C)C)NC(=O)C1OC1C(O)=O
• Target: SARS-CoV,Cysteine Protease
• Solubility: H2O:2 mg/mL (6.36 mM);DMSO:58 mg/mL (184.49 mM);Ethanol:58 mg/mL (184.49 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.36 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NSC694279, NSC-694279, Loxistatin Acid, NSC 694279, inhibit, Inhibitor, EP475, EP-475, EP 475, Cathepsin, E 64c, CysteineProtease, Cysteine Protease, Cysteine protease, SARS coronavirus, SARSCoV, SARS-CoV

Quick Database Links

Gene Symbol

SARS-CoV,Cysteine Protease