Echinatin

SKU: orb1222346

Description

Echinatin disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. Echinatin has significant antioxidant activities, it shows strong scavenging activity toward the ABTS + radical, it also dose-dependently inhibits LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells and inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells.

Key Properties

• CAS Number: 34221-41-5
• MW: 270.28
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₄O₄
• SMILES: COc2cc(O)ccc2/C=C/C(=O)c1ccc(O)cc1
• Target: Free radical scavengers
• Solubility: In Vitro: DMSO : 125 mg/mL (462.48 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Echinatin | Retrochalcone

Quick Database Links

Gene Symbol

Free radical scavengers