Efavirenz

SKU: orb1305550

Description

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in HIV-1 research. It potently inhibits viral replication in vitro and is widely employed to study antiretroviral mechanisms, drug resistance, and complex cytochrome P450-mediated metabolic interactions.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 154598-52-4
• MW: 315.67
• Purity: 99.20% (May vary between batches)
• Formula: C₁₄H₉ClF₃NO₂
• SMILES: C(#CC1CC1)[C@@]2(C(F)(F)F)C=3C(NC(=O)O2)=CC=C(Cl)C3
• Target: Autophagy,Parasite,HIV Protease,Reverse Transcriptase,Endogenous Metabolite
• Solubility: Methanol:10 mM;H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:250 mg/mL (791.97 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.34 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EFV, Efavirenz, L743726, L-743726, HIVProtease, HIV-1 RT, HIV Protease, HIV, Inhibitor, Human immunodeficiency virus, L 743726, inhibit, Autophagy, DMP 266, DMP266, DMP-266, ReverseTranscriptase, Reverse Transcriptase, Stocrin, Sustiva

Quick Database Links

Gene Symbol

Autophagy,Parasite,HIV Protease,Reverse Transcriptase,Endogenous Metabolite