Eltrombopag Olamine

SKU: orb1300431

Description

Eltrombopag Olamine is an orally bioavailable, small-molecule agonist of the thrombopoietin receptor (TPO-R/CD110). Its binding stimulates megakaryocyte proliferation and differentiation, thereby increasing platelet production. This compound is widely used in research for studying thrombopoiesis in models of immune thrombocytopenia and chemotherapy-induced myelosuppression.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 496775-62-3
• MW: 564.63
• Purity: 99.59% (May vary between batches)
• Formula: C₂₉H₃₆N₆O₆
• SMILES: NCCO.NCCO.CC1=NN(C(=O)\C1=N/Nc1cccc(-c2cccc(c2)C(O)=O)c1O)c1ccc(C)c(C)c1
• Target: Antibacterial,Thrombopoietin Receptor,Thrombin,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.77 mM);DMSO:62.5 mg/mL (110.69 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Thrombopoietin Receptor, Thrombopoietin receptor, SB497115, SB-497115, SB-497115GR, SB 497115, Promacta Olamine, Revolade, Eltrombopag, Eltrombopag diethanolamine, Eltrombopag diethanolamine salt, Eltrombopag Olamine, hepatocellular carcinomab, hematopoiesis, Inhibitor, megakaryocyte, inhibit, immune thrombocytopenia, N2C-Tpo, chimpanzee, CD34, blood platelet, Bacterial, BAF3

Quick Database Links

Gene Symbol

Antibacterial,Thrombopoietin Receptor,Thrombin,Apoptosis