Emodin

SKU: orb1304909

Description

Emodin (Frangula emodin) is a selective 11β-HSD1 inhibitor with IC50 values of 186 nM (human) and 86 nM (mouse). This compound exhibits antiviral, anti-inflammatory, and anti-cancer properties and has been shown to ameliorate metabolic disorders in diet-induced obese mice in preclinical studies.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 518-82-1
• MW: 270.24
• Purity: 94.40% (May vary between batches)
• Formula: C₁₅H₁₀O₅
• SMILES: O=C1C=2C=C(O)C=C(O)C2C(=O)C3=C(O)C=C(C=C13)C
• Target: Dehydrogenase,Autophagy,Casein Kinase,SARS-CoV
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);Acetone:7.14 mg/mL (26.42 mM);DMSO:15.3 mg/mL (56.62 mM);Ethanol:3 mg/mL (11.1 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

coronavirus, CK2, diabete, Autophagy, CaseinKinase, Casein Kinase, casein, 11β-HSD1, Emodin, Frangula emodin, insulin, SARSCoV, SARS-CoV, SARS, Spike, resistance

Quick Database Links

Gene Symbol

Dehydrogenase,Autophagy,Casein Kinase,SARS-CoV