Empagliflozin

SKU: orb1307498

Description

Empagliflozin is a potent and highly selective SGLT2 inhibitor (IC50=3.1 nM) with over 300-fold selectivity against related transporters. It is widely used in research for type 2 diabetes, facilitating in vitro mechanistic studies and in vivo models investigating glycemic control and cardiorenal outcomes.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 864070-44-0
• MW: 450.91
• Purity: 98.00% (May vary between batches)
• Formula: C₂₃H₂₇ClO₇
• SMILES: O[C@H]1[C@H](C2=CC(CC3=CC=C(O[C@H]4CCOC4)C=C3)=C(Cl)C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O
• Target: SGLT
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:8.3 mg/mL (18.41 mM);DMSO:242.5 mg/mL (537.8 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Empagliflozin, BI10773, BI-10773, BI 10773, SGLT6, SGLT4, SGLT5, SGLT, SGLT1, SGLT2, Sodium-dependent glucose cotransporters

Quick Database Links

Gene Symbol

SGLT