Ensitrelvir

SKU: orb1297924

Description

Ensitrelvir (S-217622) is an orally bioavailable 3CL protease inhibitor for SARS-CoV-2, exhibiting potent antiviral activity with an IC50 of 13 nM. It is a valuable research tool for studying coronavirus replication and has demonstrated efficacy in both in vitro assays and in vivo animal models of infection.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 2647530-73-0
• MW: 531.88
• Purity: 99.57% (May vary between batches)
• Formula: C₂₂H₁₇ClF₃N₉O₂
• SMILES: Cn1nc(cc(c(/N=C(\NC(N2Cc3nn(C)cn3)=O)/N(Cc(cc(c(F)c3)F)c3F)C2=O)c2)Cl)c2c1
• Target: SARS-CoV,Virus Protease
• Solubility: DMSO:160 mg/mL (300.82 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.52 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

S 217622, S217622, S-217622, SARS-CoV-2 3CL, SARS-CoV, SARSCoV, SARS coronavirus, Virus Protease, variant, oral, intrapulmonary replication, inhibit, Ensitrelvir, Inhibitor, COVID-19

Quick Database Links

Gene Symbol

SARS-CoV,Virus Protease