ent-Ezetimibe

SKU: orb1309701

Description

Ezetimibe is a potent cholesterol absorption inhibitor that acts by blocking the Niemann-Pick C1-like1 (NPC1L1) protein and also functions as an Nrf2 activator. Its RRS-enantiomer, ent-Ezetimibe (ent-SCH 58235), is used in research to study sterol transport and oxidative stress pathways in vitro and in vivo.

Research Area

Immunology & Inflammation; Pharmacology & Drug Discovery, Metabolism Research

Key Properties

• CAS Number: 1376614-99-1
• MW: 409.43
• Purity: 98.30% (May vary between batches)
• Formula: C₂₄H₂₁F₂NO₃
• SMILES: C(C[C@@H](O)C1=CC=C(F)C=C1)[C@H]2[C@@H](N(C2=O)C3=CC=C(F)C=C3)C4=CC=C(O)C=C4
• Target: Drug Metabolite,Others
• Solubility: DMSO:60 mg/mL (146.55 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Drug Metabolite, Inhibitor, inhibit, entEzetimibe, ent-Ezetimibe, ent-SCH 58235, ent-SCH58235, ent-SCH-58235, ent Ezetimibe, RRS-enantiomer

Quick Database Links

Gene Symbol

Drug Metabolite,Others