Enzastaurin

SKU: orb1300907

Description

Enzastaurin (LY317615) is a potent and selective PKCβ inhibitor with an IC50 of 6 nM, exhibiting 6-20 fold selectivity over PKCα, γ, and ε isoforms. It has been widely used in preclinical cancer research, including in vitro cell studies and in vivo tumor models, to investigate angiogenesis and cell signaling pathways.

Research Area

Cell Biology, Neuroscience

Key Properties

• CAS Number: 170364-57-5
• MW: 515.61
• Purity: >98%
• Formula: C₃₂H₂₉N₅O₂
• SMILES: O=C1C(C=2C=3C(N(C2)C4CCN(CC5=CC=CC=N5)CC4)=CC=CC3)=C(C(=O)N1)C=6C=7C(N(C)C6)=CC=CC7
• Target: Kinase
• Solubility: Soluble in DMSO (up to 7 mg/ml with warming)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LY-317615

Quick Database Links

Gene Symbol

Kinase