Esculetin

SKU: orb1305008

Description

Esculetin (Cichorigenin) is a natural coumarin known for its lipoxygenase (LOX) inhibitory activity, contributing to its observed anti-inflammatory and anti-tumor properties in research models. It is widely used in studies investigating inflammation, cancer, and oxidative stress pathways in both cellular and animal experiments.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 305-01-1
• MW: 178.14
• Purity: 98.03% (May vary between batches)
• Formula: C₉H₆O₄
• SMILES: OC1=C(O)C=C2C=CC(=O)OC2=C1
• Target: Lipoxygenase,PI3K,Akt
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.23 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:125 mg/mL (701.7 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cichorigenin, Akt, Aesculetin, Inhibitor, Esculetin, inhibit, Lipoxygenase, Protein kinase B, PKB, Phosphoinositide 3-kinase, PI3K

Quick Database Links

Gene Symbol

Lipoxygenase,PI3K,Akt