Etretinate

SKU: orb1300426

Description

Etretinate is an oral aromatic retinoid effective in treating psoriasis and various dermatoses. It functions by activating retinoid receptors to promote cell differentiation, suppress proliferation, and reduce inflammatory cell infiltration. This mechanism has been validated in both in vitro cellular assays and in vivo animal models of hyperproliferative skin disorders.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 54350-48-0
• MW: 354.48
• Purity: 97.89% (May vary between batches)
• Formula: C₂₃H₃₀O₃
• SMILES: CCOC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\c1c(C)cc(OC)c(C)c1C
• Target: Apoptosis
• Solubility: 10% DMSO+90% Corn Oil:2.5 mg/mL (7.05 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:65 mg/mL (183.37 mM);DMSO:65 mg/mL (183.37 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, inhibit, Ethyl etrinoate, Etretinate, Etretinato, Inhibitor, Retinoid, Ro 10-9359, Tegison

Quick Database Links

Gene Symbol

Apoptosis