Flumethasone

SKU: orb1309688

Description

Flumethasone (RS-2177) is a synthetic glucocorticoid receptor agonist used in research for its potent anti-inflammatory, antipruritic, and vasoconstrictive effects. It is applied in pharmacological studies to investigate corticosteroid signaling and related pathways in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 2135-17-3
• MW: 410.45
• Purity: 99.38% (May vary between batches)
• Formula: C₂₂H₂₈F₂O₅
• SMILES: [H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
• Target: Antifungal,Glucocorticoid Receptor,Interleukin,Nrf2,TNF
• Solubility: DMSO:55 mg/mL (134 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.87 mM);Ethanol:6 mg/mL (14.62 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, NSC 54702, NSC54702, NSC-54702, Inhibitor, Flumetasone, Flumethasone, GlucocorticoidReceptor, Glucocorticoid Receptor, RS 2177, RS2177, RS-2177

Quick Database Links

Gene Symbol

Antifungal,Glucocorticoid Receptor,Interleukin,Nrf2,TNF