Fluticasone (propionate)

SKU: orb1310855

Description

Fluticasone propionate is a potent and selective glucocorticoid receptor (GR) agonist, derived from the anti-asthmatic fluticasone. It is widely used in research to study GR signaling and anti-inflammatory mechanisms in both cellular (in vitro) and animal (in vivo) experimental models.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 80474-14-2
• MW: 500.57
• Purity: 98.98% (May vary between batches)
• Formula: C₂₅H₃₁F₃O₅S
• SMILES: O(C(CC)=O)[C@@]1(C(SCF)=O)[C@]2(C)[C@@](C[C@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[H])[H]
• Target: Virus Protease,Endogenous Metabolite,Estrogen/progestogen Receptor,Glucocorticoid Receptor,ADC Cytotoxin,Phospholipase
• Solubility: DMSO:250 mg/mL (499.43 mM);10% DMSO+90% Corn Oil:2.5 mg/mL (4.99 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cytosolic PLA2, Endogenous Metabolite, corticosteroid, anti-inflammatory, asthma, CCI 187881, CCI187881, CCI-187881, bronchial, allergic, ADCCytotoxin, ADC Cytotoxin, Glucocorticoid Receptor, GlucocorticoidReceptor, Estrogen Receptor, EstrogenReceptor, Fluticasone, Fluticasone (propionate), Fluticasone propionate, Fluticasone Propionate, EndogenousMetabolite, Enterovirus, ER, Inhibitor, HEVs, HEV, HRVs, HRV, inhibit, Mineralocorticoid Receptor, Virus Protease, VirusProtease, rhinitis, Rhinovirus, progestogenReceptor, seasonal, perennial, progestogen Receptor

Quick Database Links

Gene Symbol

Virus Protease,Endogenous Metabolite,Estrogen/progestogen Receptor,Glucocorticoid Receptor,ADC Cytotoxin,Phospholipase