Gemcitabine

SKU: orb1310791

Description

Gemcitabine (LY188011) is a synthetic nucleoside analog that inhibits DNA synthesis, exhibiting antitumor activity by inducing both autophagy and apoptosis. It is widely used in cancer research, including in vitro cell studies and in vivo models for pancreatic, lung, and breast carcinomas.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 95058-81-4
• MW: 263.20
• Purity: 98.66% (May vary between batches)
• Formula: C₉H₁₁F₂N₃O₄
• SMILES: NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
• Target: Autophagy,Nucleoside Antimetabolite/Analog,DNA/RNA Synthesis,Apoptosis
• Solubility: DMSO:125 mg/mL (474.92 mM);Ethanol:12.5 mg/mL (47.49 mM);H2O:6.25 mg/mL (23.75 mM);5% DMSO+95% Saline:0.75 mg/mL (2.85 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RNA Synthesis, RNASynthesis, Inhibitor, Gemcitabine, inhibit, NSC 613327, NSC613327, NSC-613327, LY188011, LY-188011, LY 188011, Nucleoside Antimetabolite/Analog, NucleosideAntimetabolite, Nucleoside Antimetabolite, Apoptosis, Analog, Autophagy, DNA/RNA Synthesis, DNA synthesis, DNA Synthesis, DNASynthesis

Quick Database Links

Gene Symbol

Autophagy,Nucleoside Antimetabolite/Analog,DNA/RNA Synthesis,Apoptosis