Gemfibrozil

SKU: orb1308681

Description

Gemfibrozil is a PPARα agonist that promotes fatty acid oxidation and lipoprotein lipase synthesis, enhancing triglyceride clearance and reducing apoC-III and VLDL-C. It also increases apoA-I/A-II expression to raise HDL-C. This fibric acid derivative is used in research on dyslipidemia, atherosclerosis, and metabolic syndrome in both cellular and animal models.

Research Area

Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 25812-30-0
• MW: 250.33
• Purity: 98.59% (May vary between batches)
• Formula: C₁₅H₂₂O₃
• SMILES: CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
• Target: PPAR,Cytochromes P450,Adrenergic Receptor
• Solubility: DMSO:250 mg/mL (998.68 mM);Ethanol:47 mg/mL (187.75 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.99 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Lopid, inhibit, Jezil, Gemfibrozil, Inhibitor, CI 719, CI719, CI-719, Decrelip, Cytochrome P450, CYPs, CYP1A2, CYP2C9, AdrenergicReceptor, Adrenergic Receptor, Peroxisome proliferator-activated receptors, PPAR, PPARα

Quick Database Links

Gene Symbol

PPAR,Cytochromes P450,Adrenergic Receptor