Grazoprevir

SKU: orb1302768

Description

Grazoprevir is a macrocyclic protease inhibitor targeting the HCV NS3/4A protein. It is utilized in research, notably in combination with elbasvir, to study antiviral mechanisms and efficacy in both in vitro assays and in vivo models of hepatitis C virus infection.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 1350514-68-9
• MW: 766.9
• Purity: 99.36% (May vary between batches)
• Formula: C₃₈H₅₀N₆O₉S
• SMILES: [H][C@@]12C[C@@]1([H])OC(=O)N[C@]([H])(C(=O)N1C[C@@]([H])(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1)Oc1nc3cc(OC)ccc3nc1CCCCC2)C(C)(C)C
• Target: SARS-CoV,HCV Protease
• Solubility: DMSO:125 mg/mL (162.99 mM);Ethanol:15 mg/mL (19.56 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.61 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, MK5172, MK-5172, MK 5172, Inhibitor, HCV, HCV NS3/4A protease, HCVProtease, HCV Protease, Hepatitis C virus, gt1a, gt1b, Grazoprevir, SARS coronavirus, SARSCoV, SARS-CoV

Quick Database Links

Gene Symbol

SARS-CoV,HCV Protease