GSK-4716

SKU: orb1301719

Description

GSK4716 is a small molecule agonist of the ERRβ and ERRγ receptors with an IC50 of 2 μM, demonstrating potency comparable to endogenous protein ligands. This compound is a valuable research tool for investigating ERR-mediated transcriptional regulation in metabolic, neurodegenerative, and cancer-related studies using both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 101574-65-6
• MW: 282.34
• Purity: 98.00% (May vary between batches)
• Formula: C₁₇H₁₈N₂O₂
• SMILES: CC(C)c1ccc(\C=N\NC(=O)c2ccc(O)cc2)cc1
• Target: Estrogen Receptor/ERR
• Solubility: DMSO:100 mg/mL (354.18 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.17 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, GSK 4716, GSK4716, GSK-4716, Estrogen Receptor/ERR, EstrogenReceptor, Estrogen Receptor, ERR, ERRβ/γ

Quick Database Links

Gene Symbol

Estrogen Receptor/ERR