GSK-1016790A

SKU: orb1300410

Description

GSK1016790A is a potent and selective TRPV4 channel agonist, demonstrating an EC50 of 34 nM in choroid plexus cells. This tool compound is widely used in cardiovascular, pulmonary, and renal research, facilitating the study of TRPV4's role in vitro and in animal models of edema, pain, and mechanosensation.

Research Area

Neuroscience

Key Properties

• CAS Number: 942206-85-1
• MW: 655.6
• Purity: >98%
• Formula: C₂₈H₃₂Cl₂N₄O₆S₂
• SMILES: CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(CC1)C(=O)[C@H](CO)NS(=O)(=O)c1ccc(Cl)cc1Cl
• Target: Ion channel
• Solubility: Soluble in DMSO (up to 10 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CalciumChannel, Calcium Channel, kidney, mTRPV4, HEK, GSK 101, GSK-101, GSK1016790A, GSK-1016790A, hTRPV4, potential, vanilloid, transient, Transient receptor potential channels, TRPVChannel, TRPChannel, TRPV Channel, TRP Channel

Quick Database Links

Gene Symbol

Ion channel