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GSK2018682

SKU: orb1220323

Description

GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2respectively).(In Vitro):GSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4.

Images & Validation

Key Properties

CAS Number1034688-30-6
MW440.88
Purity>98% (HPLC)
FormulaC22H21ClN4O4
SMILESCC(C)Oc1ncc(-c2nc(-c3cccc4c3ccn4CCCC(=O)O)no2)cc1Cl
TargetS1P Receptor
SolubilityDMSO:125 mg/mL (283.52 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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GSK2018682 (orb1220323)

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