GSK256073

SKU: orb1308250

Description

GSK256073 is a potent, orally bioavailable, and non-flushing full agonist of the hydroxy-carboxylic acid receptor 2 (HCA2/GPR109A). It acutely improves glucose homeostasis by inhibiting lipolysis, making it a valuable research tool for studying metabolic disorders such as type 2 diabetes and dyslipidemia in both in vitro and in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 862892-90-8
• MW: 256.69
• Purity: 98.03% (May vary between batches)
• Formula: C₁₀H₁₃ClN₄O₂
• SMILES: CCCCCn1c2nc(Cl)[nH]c2c(=O)[nH]c1=O
• Target: GPCR
• Solubility: 10% DMSO+90% Corn Oil:1.5 mg/mL (5.84 mM);DMSO:16.67 mg/mL (64.94 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, GPR109A, GPR109A (G-protein coupled receptor 109A), glucose, GSK 256073, GSK256073, GSK-256073, GPCR, HCAR2, HCA2, HCA2 (hydroxy-carboxylic acid receptor 2), HM74A, mellitus, homeostasis, dyslipidaemia, diabete, PUMA-G, type 2, T2DM

Quick Database Links

Gene Symbol

GPCR