GSK5182

SKU: orb1298992

Description

GSK5182 is a potent and selective inverse agonist of estrogen-related receptor γ (ERRγ), exhibiting an IC50 of 79 nM. This small molecule is a valuable research tool for studying ERRγ's role in metabolic regulation, energy homeostasis, and related diseases in both cellular and animal models.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 877387-37-6
• MW: 417.54
• Purity: 97.63% (May vary between batches)
• Formula: C₂₇H₃₁NO₃
• SMILES: C(=C(/CCCO)\C1=CC=CC=C1)(\C2=CC=C(OCCN(C)C)C=C2)/C3=CC=C(O)C=C3
• Target: Estrogen/progestogen Receptor,ROS,Reactive Oxygen Species,Estrogen Receptor/ERR
• Solubility: DMSO:80 mg/mL (191.6 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Reactive Oxygen Species, ReactiveOxygenSpecies, progestogen Receptor, progestogenReceptor, inhibit, Inhibitor, ERR, ERRγ, GSK 5182, Estrogen Receptor, Estrogen Receptor/ERR, EstrogenReceptor, GSK5182, GSK-5182

Quick Database Links

Gene Symbol

Estrogen/progestogen Receptor,ROS,Reactive Oxygen Species,Estrogen Receptor/ERR