GW-870086

SKU: orb1308240

Description

GW-870086 is a potent glucocorticoid receptor agonist with anti-inflammatory activity, demonstrating a pIC50 of 10.1 in NF-κB reporter assays using A549 cells. It is a valuable research tool for studying glucocorticoid receptor signaling and inflammation in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 827319-43-7
• MW: 559.64
• Purity: 99.63% (May vary between batches)
• Formula: C₃₁H₃₉F₂NO₆
• SMILES: [H][C@@]12C[C@@H](C)[C@](OC(=O)C3C(C)(C)C3(C)C)(C(=O)OCC#N)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
• Target: Glucocorticoid Receptor
• Solubility: DMSO:11 mg/mL (19.66 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.57 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, GW870086, GW-870086, GW 870086, GlucocorticoidReceptor, Glucocorticoid Receptor, glucocorticoid receptor, glucocorticoid receptor, A549 NF-κB cells, inhibit

Quick Database Links

Gene Symbol

Glucocorticoid Receptor