HSF1A

SKU: orb1226824

Description

A small molecule human HSF1 (heat shock transcription factor 1) activator; activates HSF1 in mammalian and fly cells, elevates protein chaperone expression, ameliorates protein misfolding and cell death in polyQ-expressing neuronal precursor cells and protects against cytotoxicity in a fly model of polyQ-mediated neurodegeneration; also interacts with components of the TRiC/CCT complex.

Key Properties

• CAS Number: 1196723-93-9
• MW: 409.522
• Purity: >98% (HPLC)
• Formula: C₂₁H₁₉N₃O₂S₂
• SMILES: O=S(C1=CC=C(CC)C=C1)(NC2=CC(C3=CC=CS3)=NN2C4=CC=CC=C4)=O
• Target: HSP
• Solubility: DMSO: ≥150 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

HSF1 activator

Quick Database Links

Gene Symbol

HSP