HSP27 inhibitor J2

SKU: orb1299957

Description

J2 is a small molecule inhibitor of heat shock protein 27 (HSP27). It disrupts the formation of large HSP27 polymers, thereby blocking its chaperone function and compromising cellular stress protection. This inhibitor is a valuable research tool for studying HSP27's role in cancer and neurodegenerative disease models, both in vitro and in vivo.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2133499-85-9
• MW: 264.3
• Purity: 98.00% (May vary between batches)
• Formula: C₁₃H₁₂O₄S
• SMILES: Cc1cc(=O)c2c(O)cc(OCC3CS3)cc2o1
• Target: HSP
• Solubility: DMSO:20.83 mg/mL (78.81 mM);10% DMSO+90% Corn Oil:2 mg/mL (7.57 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, HSP27 inhibitor J2, HSP-27 inhibitor J2, HSP27, Heat shock proteins, HSP, J2, J-2, J 2, inhibit

Quick Database Links

Gene Symbol

HSP