α-Humulene

SKU: orb1297468

Description

α-Humulene, a sesquiterpene isolated from Salvia officinalis essential oil, exhibits antitumor and anti-inflammatory properties. Its mechanisms involve suppressing tumor cell proliferation and modulating inflammatory pathways by inhibiting TNF-α production and downregulating COX-2 and iNOS expression, as demonstrated in various in vitro and in vivo research models.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience

Key Properties

• CAS Number: 6753-98-6
• MW: 204.35
• Purity: 97.18% (May vary between batches)
• Formula: C₁₅H₂₄
• SMILES: C\C1=C/CC(C)(C)\C=C\C\C(C)=C\CC1
• Target: NO Synthase,COX,TNF,NOS
• Solubility: Ethanol:Soluble;10% DMSO+90% Corn Oil:2.5 mg/mL (12.23 mM);DMSO:50 mg/mL (244.68 mM);Ether:Soluble

Storage & Handling

• Storage: store at low temperature,keep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclooxygenase, COX, a-Humulene, alpha-Humulene, Alpha-caryophyllene, a-caryophyllene, Humulene, iNOS, Inhibitor, NO Synthase, Nitric oxide synthases, inhibit, NOS, TNF-α, α-Caryophyllene, α-caryophyllene, α Humulene, αHumulene, α-Humulene

Quick Database Links

Gene Symbol

NO Synthase,COX,TNF,NOS