Imatinib mesylate

SKU: orb1307991

Description

Imatinib Mesylate is an orally active, multi-targeted tyrosine kinase inhibitor that potently suppresses BCR-ABL, PDGFR, and c-Kit. It is a foundational research tool for studying oncogenic signaling and has demonstrated efficacy in both in vitro assays and in vivo models of chronic myeloid leukemia and other cancers.

Research Area

Cell Biology

Key Properties

• CAS Number: 220127-57-1
• MW: 493.62 ∙ 96.11
• Purity: >98%
• Formula: C₂₉H₃₁N₇O ∙ CH₃SO₃H
• SMILES: CS(O)(=O)=O.CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1
• Target: Kinase
• Solubility: Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Gleevec; STI571

Quick Database Links

Gene Symbol

Kinase