Isoliquiritin apioside

SKU: orb1303651

Description

Isoliquiritin apioside, a compound from Glycyrrhizae radix, inhibits PMA-induced MMP9 activity, MAPK/NF-κB signaling, and reduces cancer cell invasiveness and angiogenesis. It also shows potential against oxidative stress-induced genotoxicity, supporting its use in oncology and molecular pharmacology research for in vitro mechanistic studies.

Research Area

Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 120926-46-7
• MW: 550.51
• Purity: 98.84% (May vary between batches)
• Formula: C₂₆H₃₀O₁₃
• SMILES: [H][C@]1(O[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@H](Oc2ccc(\C=C\C(=O)c3ccc(O)cc3O)cc2)O[C@H](CO)[C@@H](O)[C@@H]1O
• Target: MMP,p38 MAPK,NF-κB
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.63 mM);DMSO:33.3 mg/mL (60.49 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

p38MAPK, p38 MAPK, Isoliquiritin apioside, Inhibitor, inhibit, NF-kB, NFκB, NFkB, MMP, Nuclear factor-κB, Nuclear factor-kappaB, NF-κB, metastasis, HT1080, HIF-1α, MAPK, Matrix metalloproteinases, angiogenesis, cancer

Quick Database Links

Gene Symbol

MMP,p38 MAPK,NF-κB