Isotretinoin

SKU: orb1308025

Description

Isotretinoin (13-cis-Retinoic acid) is a natural retinoic acid that activates nuclear RARs to modulate gene expression, promoting cellular differentiation and apoptosis. It is widely used in oncology, dermatology, and immunology research, demonstrating antineoplastic, anti-inflammatory, and keratinization-inhibiting effects in both in vitro and in vivo studies.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 4759-48-2
• MW: 300.44
• Purity: 97.01% (May vary between batches)
• Formula: C₂₀H₂₈O₂
• SMILES: C(=C/C(=C/C=C/C(=C\C(O)=O)/C)/C)\C=1C(C)(C)CCCC1C
• Target: Retinoid Receptor,Endogenous Metabolite,Autophagy
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.66 mM);Ethanol:1 mg/mL (3.33 mM);DMSO:250 mg/mL (832.11 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

13-cis-Retinoic acid, anticancer, Autophagy, Inhibitor, EndogenousMetabolite, Endogenous Metabolite, orally active, Isotretinoin, inhibit, severe acne, RAR/RXR, RAR, Retinoic acid receptors, Retinoid Receptor, Retinoid X receptors, RetinoidReceptor, vitamin A

Quick Database Links

Gene Symbol

Retinoid Receptor,Endogenous Metabolite,Autophagy