Isoxsuprine hydrochloride

SKU: orb1224599

Description

A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor. (In Vitro):Results show that Isoxsuprine hydrochloride inhibits circular chemorepellent induced defect (CCID) formation dose dependently (5 to 60 μM) and also inhibits 12(S)-HETE synthesis. Furthermore, Isoxsuprine hydrochloride is the only drug inhibiting the induction of all three mobility markers (MLC2, MYPT and paxillin).(In Vivo):Total infarct volume in vehicle-treated animals is 279±25 mm3 compare to 137±18 mm3 in Isoxsuprine hydrochloride-treated animals.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 579-56-6
• MW: 337.84
• Purity: >98% (HPLC)
• Formula: C₁₈H₂₄ClNO₃
• SMILES: Cl.CC(COC1=CC=CC=C1)NC(C)C(O)C1=CC=C(O)C=C1
• Target: Adrenergic Receptor
• Solubility: Soluble in Water

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Adrenergic Receptor