Ivermectin

SKU: orb1309664

Description

Ivermectin (MK-933) is a research compound that acts as an agonist of glutamate-gated chloride channels (GluCls), leading to its well-characterized antiparasitic effects. It is widely used in in vitro and in vivo studies of parasitology and neuropharmacology to investigate ion channel function and anthelmintic mechanisms.

Research Area

Cell Biology, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 70288-86-7
• MW: 875.1
• Purity: >98%
• Formula: C₄₈H₇₄O₁₄ (B₁a form)
• SMILES: CO[C@H]1C[C@H](O[C@H]2[C@H](C)O[C@H](C[C@@H]2OC)O[C@H]2[C@@H](C)\C=C\C=C3/CO[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]5C[C@@H](C\C=C2/C)O[C@@]2(CC[C@H](C)[C@H](O2)C(C)C)C5)[C@]34O)O[C@@H](C)[C@@H]1O.CC[C@@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]1C[C@@H](C\C=C(C)\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\C=C\C=C3/CO[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O1)[C@]34O)O2
• Target: SARS-CoV,Parasite,Antibacterial,Antibiotic,HIV Protease,GluCls,P2X Receptor,Anti-infection,Mitophagy,HSV,Autophagy
• Solubility: Soluble in DMSO (40 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

22,23-Dihydro C076B1; MK-933

Quick Database Links

Gene Symbol

SARS-CoV,Parasite,Antibacterial,Antibiotic,HIV Protease,GluCls,P2X Receptor,Anti-infection,Mitophagy,HSV,Autophagy