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IWP-2

SKU: orb1224243

Description

IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses.

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Key Properties

CAS Number686770-61-6
MW466.6
Purity>98% (HPLC)
FormulaC22H18N4O2S3
SMILESO=C(NC1=NC2=CC=C(C)C=C2S1)CSC3=NC(CCS4)=C4C(N3C5=CC=CC=C5)=O
TargetWnt/beta/catenin
SolubilityDMF: 22 mg/mL warming (47.14 mM); DMSO: 4 mg/mL warming (8.57 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor of Wnt Production-2

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IWP-2 (orb1224243)

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5 mg
$ 80.00
10 mg
$ 110.00
25 mg
$ 180.00
50 mg
$ 310.00
100 mg
$ 460.00
200 mg
$ 680.00
500 mg
$ 1,100.00