JHU37160

SKU: orb1298442

Description

JHU37160 is a potent and selective DREADD agonist, exhibiting high affinity and efficacy at both hM3Dq and hM4Di receptors. This tool compound is widely used in neuroscience research for the chemogenetic manipulation of specific neuronal circuits in both in vitro cellular assays and in vivo animal models to study behavior and neural function.

Research Area

Neuroscience

Key Properties

• CAS Number: 2369979-68-8
• MW: 358.84
• Purity: 99.25% (May vary between batches)
• Formula: C₁₉H₂₀ClFN₄
• SMILES: CCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2c(F)cccc12
• Target: AChR
• Solubility: DMSO:72 mg/mL (200.65 mM);Ethanol:72 mg/mL (200.65 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.57 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Clozapine, DREADD, M3 mAChR, mAChR, Inhibitor, Muscarinic acetylcholine receptor, JHU37160, JHU-37160, JHU 37160, inhibit, hM3Dq, hM4Di

Quick Database Links

Gene Symbol

AChR