Karacoline

SKU: orb1297311

Description

Karacolinem is a natural small molecule that inhibits extracellular matrix degradation in intervertebral disc degeneration by targeting the NF-κB signaling pathway. It is a useful research tool for studying IDD mechanisms in both cellular and animal models of disc degeneration.

Research Area

Signal Transduction

Key Properties

• CAS Number: 39089-30-0
• MW: 377.52
• Purity: 99.64% (May vary between batches)
• Formula: C₂₂H₃₅NO₄
• SMILES: [H][C@]12C[C@]3([H])[C@]([H])([C@H]1O)[C@](O)(C[C@@H]2OC)C1C[C@@]2([H])C33C1N(CC)C[C@]2(C)CC[C@@H]3O
• Target: NF-κB
• Solubility: DMSO:30 mg/mL (79.47 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.3 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NFkB, NF-κB, NFκB, NF-kB, Karacoline, inhibit, Inhibitor

Quick Database Links

Gene Symbol

NF-κB